Protein splicing is an extraordinary post‐translational reaction that removes an intact central “spacer” domain (Sp) from precursor proteins (N‐Sp‐C) while splicing together the N‐ and C‐domains of the precursor, via a peptide bond, to produce a new protein (N‐C). All of the available data on protein splicing fit a model in which these intervening sequences excise at the protein level via a self‐splicing mechanism. Several proteins have recently been discovered that undergo protein splicing, and in two such cases, the excised (...) spacer protein is an endonuclease. Such endonucleases are capable of conferring genetic mobility upon the intervening sequences that encodes them. These intervening sequences define a new family of mobile genetic elements that are translated yet remain phenotypically silent by excising at the protein rather than the RNA level. (shrink)

The circumscribed quadrature of professional ethics aims to show the necessary shift from deontology to professional ethics, from deontological codes to ethical codes. While deontology and the deontological codes that materialise from it set their sights on professionals' responsibilities, professional ethics and the ethical codes that should derive from it would set their sights on the professional act, on its successful performance. In this way, the stress comes to be placed not only on the professional's responsibility, although that too, but (...) also on the necessary orchestration of the responsibilities shared at numerous levels by everyone involved in the performance of the professional act. The author identifies and typifies five elements present in the professional act. Four of them involve direct the protagonism of the professional, the recipient of the professional service, the institution that makes the service possible and from which the professionals' service is offered, and finally the human factor, the people who are behind the aforementioned factors and their nature, the professional, the recipient of the services and institutions. And each of these factors paves the way for a series of diversified protagonisms: inter-professional cooperation, receiver of professional services and their human environment around them, macro and micro institutions, diverse human profiles. However, all of this takes place within the framework of the fifth important element in professional ethics: a given, specific society as a circumscription of the four elements cited above, which sets the moral bar, a set of convictions and desired collective ethics which unquestionably also affect the performance of professional acts. With this reflection, we take note of the necessary co-responsibility in the provision of professional services, a co-responsibility which we could express simply in healthcare terms: it is not enough to merely have sound healthcare professionals if we do not have good patients with favourable affective environments, nor sound healthcare institutions, nor serious people who are socially committed to their work and their role, nor a society that believes in and fosters given identifiers of the personal and professional health to which we aim. The reflections in this proposal embark on a pathway of reflection which, we believe, deserves to be further explored. (shrink)

This paper takes Franco's Spain to be a powerful case study for analyzing the ways in which power shapes science and technology and is shaped by them in return. Spain was the last country in Western Europe to establish closer links with any of the international cooperative institutions emerging after WWII. As such, developments internal to Spanish society were quite autonomous and relatively free from foreign influences. The paper focuses first on the brand new, powerful institution that the Francoist regime (...) created to promote scientific research under tight political control, the Consejo Superior de Investigaciones Científicas. Next it turns to applied science and technology, top priorities for the regime's state-supported programs of industrialization. They were implemented through the politically and financially powerful Instituto Nacional de Industria. Using diplomatic sources, the paper next argues that, until the late 1950s, Spain maintained substantial political and economic isolation essentially because the regime bet on autarkic policies and a model of largely isolated development. In this model, it was crucial for the regime to develop its own technological and scientific resources. Finally, the paper examines how the regime fostered a new Spanish identity in which science had a new role. (shrink)

Katz (1981, 1985) has denied the psychological import of Linguistics on the grounds of alleged inconsistencies that arise when Linguistics is conceived as a psychological enterprise, and proposed an alternative Platonistic conception. The paper discards the plausibility of this latter approach to the study of natural language but recognizes the difficulties Katz has pointed out. It is claimed that these difficulties appear if the “strong competence hypothesis” (Bresnan & Kaplan, 1982) is assumed, that is, if it is assumed that the (...) form of the speaker’s knowledge of language is that of a grammar. A weaker conception of the psychological relevance of linguisitic theories is proposed-one that avoids Katz’s difficulties, is more congenial to Chomsky, and clears the way for a fruitful cooperation between Linguistics and Psycholinguistics. (shrink)

SummaryIn early and prehistoric times, human groups cooperated among themselves and competed viciously with other groups. Concepts of international relations, notably universal hegemony and exclusive nationalism, go back to the earliest recorded history. Only the ancient Greeks experienced inter-state relations somewhat analogous to those of modern Europe; and the first reflections on these may be found in Thucydides. The Greeks, and later the Romans, above all Cicero, developed a notion of cosmopolitanism. During the Latin Middle Ages, the papacy perpetuated the (...) idea of universal hegemony. The principle of state sovereignty was also formulated. The pre-modern Chinese empire was held to rule ‘all-under-Heaven’; Confucian ethics contributes the notion of humanity as the fundamental category. Muslims deepened the us–them distinction by claiming sole legitimacy for their religious community under the Caliph. Today, Muslims veer between this and a more Western approach to international relations. (shrink)

A cross-cultural analysis of trust and cooperation networks in Northern Ghana (NGHA) and Oaxaca (OAX) was carried out by means of ego networks and interviews. These regions were chosen because both are inhabited by several ethnic groups, thus providing a good opportunity to test the cultural group selection hypothesis. Against the predictions of this approach, we found that in both regions cooperation is grounded in personal trust groups, and that social cohesion depends on these emotional bonds. Moreover, in agreement with (...) Fiske's notion of “evolved proclivities”, we also found two distinct kinds of trust networks, one for each region, which vary in terms of the degree of ethnic interrelation. This pattern suggests that social cohesion increases when environmental resources are scarce. (shrink)

The paper presents the territorial and axiological context and the peculiarities of the participatory project developed by the Polis Research Centre and the Bon Pastor Neighbourhood Association, as well as the first steps in the design of two interventions. The first intervention, the Wall and Party Walls in Rodriguez de la Fuente Square, is proposed within the framework of the sustainable development strategies of Barcelona City Council. Its main objective is to achieve thermal insula­tion of the affected dwellings, thus contributing (...) to the well being of the residents and to the reduc­tion of CO 2 emissions into the atmosphere. Besides, it is aimed to solve landscape discontinuity. In the lower part of the party walls, there is a wall, a kind of plinth that the residents have chosen as a site for the expansion of the work on the civic remembrance of the neighbourhood. There, the “Living Memory” space will be set up, reserved for interventions by children from the quarter’s schools through a work programme run in cooperation with them. The second intervention is the case of the centennial Mulberry Tree classified as a tree of local interest. In 2018, the mulberry tree suffered some damage from thugs who threw firecrackers inside. Therefore, the need was pointed out to reorganise the space around the tree in order to create dissuasive effects and preserve its integrity. These are preliminary studies to be discussed by the agents involved in the project: the Sant Andreu District, the IMPUQV (Institut Municipal del Paisatge Urbài la Qualitat de Vida), and the Bon Pastor Neighbourhood Association. (shrink)

RESUMENEn esta contribución pretendemos reivindicar la necesidad de tener en cuenta las relaciones de confianza a la hora de tratar de entender la evolución de la cooperación. En este artículo, tras motivar el interés de tener en cuenta el papel de la confianza en la evolución de la cooperación, revisamos el concepto de confianza, como una actitud compleja que presupone vinculación afectiva y expectativas normativas, y proponemos una tipología que permite ordenar su variedad. Sostenemos que la complejidad de la cooperación (...) humana tiene que ver con la manera en que los homínidos desarrollaron el andamiaje psicológico que hizo posible la confianza, y tratamos de proponer un escenario de su origen.PALABRAS CLAVECONFIANZA, COOPERACIÓN, EVOLUCIÓN SOCIALABSTRACTIn this paper we contend that trust has to be taken into account to explain the evolution of human cooperation. After showing that current models within evolutionary game theory overlook the role of trust, we offer our understanding of this concept, as a complex attitude that involves affective filiations and normative expectations, and put forward a typology of kinds of trust. We argue that the complexity of human cooperation was made possible in the psychological scaffolding that characterizes hominid evolution and made trust relationships possible. We also advance an hypothesis about the origin of trust.KEYWORDSTRUST, COOPERATION, SOCIAL EVOLUTION. (shrink)

Human Towers are one of the most representative traditional sporting games in Catalonia, recognized in 2010 as Intangible Cultural Heritage by the United Nations Organization for Education, Science and Culture. The objective of this research was to study the emotional states elicited by a representative performance of the colla de Castellers de Lleida. This research is based on an ethnographic case study, with mixed methods in which 17 key informants voluntarily participated. Participant observation was used; the data were recorded in (...) a field diary and oral sources. The content analysis was done using the Atlas.ti software. An SPSS database was also created. The statistical techniques were: Descriptive statistical techniques, cross tables with Pearson's Chi-square values. We also used a classification and regression trees to examine the predictive capacity of five independent variables of emotional states. The results reveal that the comments were mostly oriented toward well-being states, The internal cooperative logic of the Human Towers enhances the intense interpersonal relationships of socio-emotional well-being. (shrink)

The environmental complexity in which living organisms found themselves throughout evolution, most likely resulted in various encounters that would continuously challenge the organisms' ability to survive. Coping with this stress can prove energetically demanding and might require the proper coupling between mechanisms aimed at sensing external stimuli and cellular strategies geared at producing energy. In this issue of BioEssays, Lovejoy and Hogg hypothesize that preservation of this bifaceted coupling can be detected by the maintenance and evolution of stress response mechanisms (...) at the genomic, molecular and cellular levels. Through ancestry‐tracking, they identify a group of related G protein‐coupled receptor systems with intersecting stress‐modulating properties which might represent an essential part of a complex organism's coping mechanisms to stress, an attribute that they suspect may be affected in individuals suffering from mood disorders such as depression. (shrink)

Our concept of disorder is changing. This causes problems for projects of descriptive conceptual analysis. Conceptual change means that a criterion that was necessary for a condition to be a disorder at one time may cease to be necessary a relatively short time later. Nevertheless, some conceptually based claims will be fairly robust. In particular, the claim that no adequate account of disorder can appeal only to biological facts can be maintained for the foreseeable future. This is because our current (...) concept of disorder continues to be laden with ethical and political values in multiple ways. (shrink)

This book collects some of the most exciting pioneering work in perceptual and cognitive psychology. The authors' quantitative approach to the study of mental images and their representation is clearly depicted in this invaluable volume of research which presents, interprets, evaluates, and extends their work. The selections are preceded by a thorough review of the history of their experiments, and all of the articles have been updated with reviews of the current literature. The book's first part focuses on mental rotation; (...) the second includes other, more complex transformations and sequences of transformations. A third part describes work on rotational transformations in the context of the perceptual illusion of &"apparent motion.&" Roger N. Shepard is Professor of Psychology, Stanford University. Lynn A. Cooper is Professor of Psychology, University of Arizona. A Bradford Book. (shrink)

Núñez et al. (2019) argue that cognitive science has failed either “to transition to a mature inter‐disciplinary coherent field” (p. 782) or “to generate a successful [Lakatosian] research program” (p. 789). We argue that the former was never the intention of many early researchers within the field, while the latter is an inappropriate criterion by which to judge an entire discipline. However, we concur with Núñez et al. (2019) that the individual disciplinary balance within cognitive science has changed over time. (...) Of particular concern is the fact that the use of computational methods appears to be on the wane. (shrink)

The identification and valorization of unacknowledged, feminized forms of economic productivity has been an important task for feminist theory. In this article, we expand and rethink existing definitions of labour, in order to recognize the essential economic role women play in the stem cell and regenerative medicine industries, new fields of biomedical research that are rapidly expanding throughout the world. Women constitute the primary tissue donors in the new stem cell industries, which require high volumes of human embryos, oöcytes, foetal (...) tissue and umbilical cord blood. Such material is generally given for free in the advanced industrial democracies, constituted as a surplus (‘spare’ embryos) or waste (umbilical cord ‘afterbirth’, cadaveric foetuses, poor quality oöcytes) whose generative powers should not be withheld from others. At the same time, among impoverished female populations in developing nations, such biological material is now often procured through frankly transactional relations, where women undertake risky procedures for small fees. In each case, female bodily productivity is mobilized to support bioeconomic research, yet the economic value involved in these relations is largely unacknowledged. In this article, we consider both the gift economy and the transactional economy for reproductive tissues as a form of labour. In order to fully conceptualize the specificities of feminized productivity in the bioeconomy, we distinguish between earlier feminist theories of reproductive labour and the emerging practices generated by stem cell research, which we term regenerative labour. We consider how historical transformations in the regulation of feminized labour and the technical repertoires of stem cell research renegotiate the productivity limits of female reproductive biology, opening it out to novel and profitable forms of surplus value and enrolling women in complex negotiations over their role in bioeconomic activity. (shrink)

This paper contributes to inquiries into the genealogy of governmentality and the nature of secularization by arguing that pastoralism continues to operate in the algorithmic register. Drawing on Agamben’s notion of signature, I elucidate a pair of historically distant yet archaeologically proximate affinities: the first between the pastorate and algorithmic control, and the second between the absconded God of late medieval nominalism and the authority of algorithms in the cybernetic age. I support my hypothesis by attending to the signaturial kinships (...) between, on the one hand, temporality and authority in our contemporary conjuncture, and, on the other, obedience and submission in Christian thought from late antiquity and the late Middle Ages. I thereby illustrate the hidden genealogical continuities between theological-pastoral technologies of power and technocratic-algorithmic modalities of governance. I conclude by suggesting that medieval counter-conducts may be redeployed in our present circumstances for emancipatory ends. (shrink)

We report the identification of a recurrent, 520-kb 16p12.1 microdeletion associated with childhood developmental delay. The microdeletion was detected in 20 of 11,873 cases compared with 2 of 8,540 controls and replicated in a second series of 22 of 9,254 cases compared with 6 of 6,299 controls. Most deletions were inherited, with carrier parents likely to manifest neuropsychiatric phenotypes compared to non-carrier parents. Probands were more likely to carry an additional large copy-number variant when compared to matched controls. The clinical (...) features of individuals with two mutations were distinct from and/or more severe than those of individuals carrying only the co-occurring mutation. Our data support a two-hit model in which the 16p12.1 microdeletion both predisposes to neuropsychiatric phenotypes as a single event and exacerbates neurodevelopmental phenotypes in association with other large deletions or duplications. Analysis of other microdeletions with variable expressivity indicates that this two-hit model might be more generally applicable to neuropsychiatric disease. © 2010 Nature America, Inc. All rights reserved. (shrink)

Based on data from a survey of biological scientists at 125 American universities, this article explores how the commercialization of the university affects the problems academic scientists pursue and argues that this reorientation of scientific agendas results in a shift from science in the public interest to science for private goods. Drawing on perspectives from Bourdieu on how actors employ strategic practices toward the accumulation of social capital and acquire dispositional and perceptional tendencies that in turn recondition social structures, the (...) commercialization of the university is construed not as something that ‘‘happens to,’’ but rather something that ‘‘happens through’’ academic scientists. The specific shape and direction of the commercialization of the university is therefore influenced by how scientists incorporate the new resources and social relations of commercialization into their scientific practice and how their creative engagement with shifting structural conditions remakes the culture of academic science. (shrink)

The chapter challenges hyperbolic claims about the centrality of appreciation of beauty to Buddhism. Within the texts, attitudes are more mixed, except for a form of 'inner beauty' - the beauty found in the expression of virtues or wisdom in forms of bodily comportment. Inner beauty is a stable presence throughout Buddhist history, practices, and art.

This six volume Routledge Library Edition set is dedicated to the work of key nineteenth-century German thinker, Friedrich Nietzsche, whose hugely influential work in the field of philosophy continues to be felt to this day. The six volumes, published between 1948 and 1988, represent a truly wide-ranging analysis of Nietzsche’s life and work, offering an excellent overview of the cannon of critical analysis and interpretation on Nietzsche in the twentieth century. The collection covers Nietzsche’s perspectives and influence upon a variety (...) of sociological and philosophical debates, as well as placing his work in the context of contemporaries such as Richard Wagner, Fyodor Dostoyevsky and Max Stirner. (shrink)

: This article seeks to explain how thought experiments work, and also the reasons why they can fail. It is divided into four sections. The first argues that thought experiments in philosophy and science should be treated together. The second examines existing accounts of thought experiments and shows why they are inadequate. The third proposes a better account of thought experiments. According to this account, a thought experimenter manipulates her worldview in accord with the “what if” questions posed by a (...) thought experiment. When all necessary manipulations are carried through, the result is either a consistent model or a contradiction. If a consistent model is achieved, the thought experimenter can conclude that the scenario is possible; if a consistent model cannot be constructed, then the scenario is not possible. The fourth section of the article uses this account to shed light on the circumstances in which thought experiments fail. (shrink)

Social scientists have investigated many facets of popular music over the last 25 years. The vast majority of their efforts have focused on men and their contributions to the creation and performance of popular music. As a result, we know little about women and their experiences as musicians in a traditionally male-centered and male-dominated activity. In this study, the authors used in-depth interviews with 15 local-level female rock and roll musicians in two U.S. cities to explore audiences' reactions and responses (...) to them as performers and their interactions with other band members. (shrink)

God, sex, and economics are all intertwined. The trafficking of people for sex intensifies each year. The sex trade crosses a spectrum from ‘high class’ escorts to sex slaves. The sex industry includes toys, pornography, and the exchange of sex between buyers, sellers, and managers. In this market exists sexual poverty caused by injustice, the imbalance of sexual power between individuals and within structures. Poverty pushes people into the market to sell, to be sold. Theologically there is a harmful, top-down, (...) and irrelevant theology that often ignores our sexuality. Liberation theology’s hermeneutical circle, a circle of action and reflection in community, can address sexual poverty. Its steps include: 1. assessing our situation; 2. analyzing our situation with academic tools; 3. analyzing our faith; and 4. praxis; right action. It can help us to draw the line between sexual exploitation and the celebration of sex as a way to know God. (shrink)

Many students who sign up for undergraduate‐level philosophy arrive with the expectation that moral philosophy is concerned with how one should act in the concrete and familiar situations of everyday life. Yet moral philosophers are often motivated by an ideal of neutrality, and adopt a detached perspective to achieve a scientific view of the competing moral theories. To concretise the points of disagreement they present highly specific examples that are abstracted from daily reality. There is something odd about the image (...) of morality that comes into view. What kind of guidance about how to act in concrete and familiar situations can this form of theorising bring about? This paper examines Iris Murdoch’s account of moral perception as an alternative starting point. Murdoch offers a perspective that is conceptually prior to the separation of thought from action, one that addresses the agent on the level of perception. While accounts of moral perception are often criticized for proposing a complacent moral theory that is inherently conservative, I argue that Murdoch’s account offers a radical – or tragic – form of perfectionism. While moral philosophy cannot provide sufficient reasons to act, Murdoch shows that it can, like art, make us practical, capable of acting. (shrink)

By constructing a maximal incomplete d.r.e. degree, the nondensity of the partial order of the d.r.e. degrees is established. An easy modification yields the nondensity of the n-r.e. degrees and of the ω-r.e. degrees.

This is a study of Aristotle's moral philosophy as it is contained in the Nicomachean Ethics. Hardie examines the difficulties of the text; presents a map of inescapable philosophical questions; and brings out the ambiguities and critical disagreements on some central topics, inclduing happiness, the soul, the ethical mean, and the initiation of action.

The development of analogical reasoning has traditionally been understood in terms of theories of adult competence. This approach emphasizes structured representations and structure mapping. In contrast, we argue that by taking a developmental perspective, analogical reasoning can be viewed as the product of a substantially different cognitive ability – relational priming. To illustrate this, we present a computational (here connectionist) account where analogy arises gradually as a by-product of pattern completion in a recurrent network. Initial exposure to a situation primes (...) a relation that can then be applied to a novel situation to make an analogy. Relations are represented as transformations between states. The network exhibits behaviors consistent with a broad range of key phenomena from the developmental literature, lending support to the appropriateness of this approach (using low-level cognitive mechanisms) for investigating a domain that has normally been the preserve of high-level models. Furthermore, we present an additional simulation that integrates the relational priming mechanism with deliberative controlled use of inhibition to demonstrate how the framework can be extended to complex analogical reasoning, such as the data from explicit mapping studies in the literature on adults. This account highlights how taking a developmental perspective constrains the theory construction and cognitive modeling processes in a way that differs substantially from that based purely on adult studies, and illustrates how a putative complex cognitive skill can emerge out of a simple mechanism. (shrink)

Philosophers of biology claim that function talk is consistent with naturalism. Yet recent work in biology places new pressure on this claim. An increasing number of biologists propose that the existence of functions depends on the organisation of systems. While systems are part of the domain studied by physics, they are capable of interacting with this domain through organising principles. This is to say that a full account of biological function requires teleology. Does naturalism preclude reference to teleological causes? Or (...) are organised systems precisely a naturalised form of teleology? In this paper I suggest that the biology of organised systems reveals several contradictions in the main philosophical conceptions of naturalism. To integrate organised systems with naturalism’s basic assumptions—that there is no theory-independent view for metaphysics, and that nature is intelligible—I propose an idealist solution. (shrink)

Scholars often draw attention to the remarkably individual and progressive character of Kant's Universal Natural History and Theory of the Heavens. What is less often noted, however, is that Kant's project builds on several transformations that occurred in natural science during the seventeenth and eighteenth centuries. Without contextualising Kant's argument within these transformations, the full sense of Kant's achievement remains unseen. This paper situates Kant's essay within the analogical form of Newtonianism developed by a diverse range of naturalists including Georges (...) Buffon, Albrecht von Haller and Thomas Wright. It argues that Kant's universal conception of natural history can be viewed within the free-thinking and anti-clerical movement associated with Buffon. This does not mean, however, that it breaks from the methodological rules of Newtonianism. The claim of this paper is that Kant's essay contributes to the transformation of natural history from a logical system of classification to an explanation for the physical diversity of natural products according to laws. (shrink)

Public health decisions made by the state involve considerable disagreements on the course of actions, uncertainties, and compromises that arise from moral tensions between the demands of civil liberties and the goals of public health. With such complex decisions, it can be extremely difficult to arrive at and justify the best option. In this article, we propose an ethical decision-making framework based on the philosophy of Ubuntu and argue that in sub-Saharan African settings, this approach provides attractive alternative conventions of (...) moral decision-making and a useful language for understanding moral reasoning and ethics. Through its emphasis on humanity, compassion, and social responsibility, Ubuntu (“I am because we are”) has the potential to facilitate solutions to and avert conflicts between individual rights and public health. The use of Ubuntu shifts the moral reasoning and ethics of decision-making from a field of philosophy shaped by the global north, to the everyday values, decision-making, and consequent practices of people in much of Africa. Using examples of Ebola, pandemic influenza, and tuberculosis, we illustrate how Ubuntu can be applied to tackle conflicting ethical problems in public health and medicine. (shrink)

It is a commonplace of the critical innovation literature that experiment has replaced mass production as the driving force of accumulation. But while many theorists have explored the politics and dynamics of such economies of experiment under the rubric of ‘immaterial’, cognitive or affective labour, few have examined the intersection of labour, experiment and the speculative in the clinic. Taking the clinic as representative of contemporary transformations in the commodity-form, labour and innovation, this article will look at recent attempts to (...) reform the clinical trial, arguing that these developments represent a far-reaching shift in our understanding of medicine. First, I investigate recent efforts (associated with the discourse of ‘translational medicine’) to rethink the interface between experimental lab-based science and the clinic. I also look at closely associated efforts to reintroduce an element of experimental surprise into the clinical trial process itself, through the adoption of novel trial designs. If the randomized controlled trial was conceived essentially along the lines of a product testing procedure, recent efforts have attempted to reintroduce surprise into the testing process itself – in other words, to invent a trial process capable of producing unexpected events as leads for further innovation. I then move from the experimental clinic to what I call the distributed experiment. Here I focus on efforts to outsource pharmacological innovation to a distributed public of patients through the use of social networking software. These platforms allow drug developers to escape the limits of the conventional clinical trial by tracking the experimental practices taking place in the distributed clinic of unregulated drug consumption. (shrink)

In this paper I propose a new account of living natural products in Kant’s physical geography. I argue that Kant adopts Buffon’s twofold conception of natural history, which consists of a general theory of nature as a physical nexus of causes and a particular account of living natural products in the setting of the earth. Yet in contrast to Buffon, who placed the two parts of natural history on equal epistemic footing, Kant’s physical geography can be understood as a second, (...) pragmatic level of inquiry that stands under the formal conditions of nature outlined in Universal Natural History. On the higher, formal level, natural history provides a physical account of time and space as an expanding causal sequence. On the lower, pragmatic level, physical geography provides a causal account of particular natural products as developing within a specific place. I argue that this two-tiered account not only clarifies the relation between metaphysics and experience in Kant’s pre-critical philosophy, it also sheds light on the continuity between the method of physical geography and the systematisation of nature presented in the critical philosophy. (shrink)

The concept of population is central to ecology, yet it has received little attention from philosophers of ecology. Furthermore, the work that has been done often recycles ideas that have been developed for evolutionary biology. We argue that ecological populations and evolutionary populations, though intimately related, are distinct, and that the distinction matters to practicing ecologists. We offer a definition of ecological population in terms of demographic independence, where changes in abundance are a function of birth and death processes alone. (...) However, demographic independence is insufficient on its own so we supplement it with the idea of shared habitat. An ecological population is a group of organisms of the same species in a habitat that manifests DI. Given the importance of metapopulation dynamics to modern ecology, an account of ecological population must apply to this domain as well. Thus, we extend our definition of ecological population to the metapopulation. To facilitate the extension, we introduce the metahabitat—a collection of spatially segregated habitat patches shared by a single DI population. This enables us to diagnose some unhelpful trends in the metapopulation literature and emphasize the importance of habitat dynamics in pursuit of the goals of theoretical ecology and conservation biology. (shrink)

In this paper, I explore a prominent question of Hericlitean scholarship: how is change possible? Karl Popper and G. S. Kirk tackle this same question. Kirk asserts that Heraclitus believed that change is present on a macrocosmic level and that all change is regulated by the cosmic principle logos. Popper, on the other hand, claims Heraclitus believed that change is microcosmic and rejected that all change is regulated by logos. I argue for a combination of aspects from each of their (...) claims and conclude that change is present both microcosmically and macrocosmically and that all change is governed by logos . (shrink)

Environmental health remains a niche topic in bioethics, despite being a prominent social determinant of health. In this paper we argue that if bioethicists are to take the project of health justice as a serious one, then we have to address environmental injustices and the threats they pose to our bioethics principles, health equity, and clinical care. To do this, we lay out three arguments supporting prioritizing environmental health in bioethics based on bioethics principles including a commitment to vulnerable populations (...) and justice. We also highlight and advocate for environmental law efforts that align with these priorities, focusing specifically on the need for a right to a healthy environment. Our intention is to draw attention to the legal and ethical concepts that underlie the importance of a healthy environment, and urge bioethicists to prioritize both legal and ethical advocacy against environmental injustices in their practice. (shrink)

In this article, I compare and evaluate R. D. Laing and A. Esterson’s account of schizophrenia as developed in Sanity, Madness and the Family, social models of disability, and accounts of extended mental disorder. These accounts claim that some putative disorders should not be thought of as reflecting biological or psychological dysfunction within the afflicted individual, but instead as external problems. In this article, I consider the grounds on which such claims might be supported. I argue that problems should not (...) be located within an individual putative patient in cases where there is some acceptable test environment in which there is no problem. A number of cases where such an argument can show that there is no internal disorder are discussed. I argue, however, that Laing and Esterson’s argument—that schizophrenia is not within diagnosed patients—does not work. The problem with their argument is that they fail to show that the diagnosed women in their study function adequately in any environment. (shrink)

The politics of precarity have emerged on the contemporary scene of critical theory with great social force in recent years. This paper looks at the risks and obstacles of positing precariousness and vulnerability as the basis of a universal ethics while also arguing for the socially transformative potential of such a model. More broadly, it considers the crucial question of what stands in the way of human relation and ethical life in an age of neoliberalism and biopolitics, and posits an (...) ethics of resemblance grounded in the commonality of flesh and in the at once singular and universal experience of loss. (shrink)

Emmanuel Levinas never wrote about cinema. To the uninitiated, this may appearsurprising, given that his life spanned the twentieth century, in which film emerged as amajor art form, and his work includes tantalising allusions to films and the cinematicmedium. Far from surprising, however, the liminal place that cinema occupies inLevinas’s thought is entirely understandable. Although his philosophy features manycultured references to literature and the other arts, and he discusses the work of suchwriters as Marcel Proust and Michel Leiris in some (...) detail, his early work is dismissive ofthe aesthetic dimension in ethical terms. More significantly still, his philosophy bears achallenging relation to questions of vision and the phenomenological world ofappearance, tending towards the anti-ocular and revealing an iconoclastic approach toimages. There is something provocative, then, in wanting to ask what Levinas’sphilosophy has to say about cinema, if we understand this realm as the location parexcellence of the moving image. Yet this is precisely the guiding question of this SpecialIssue, which is the first to bring together articles on the work of Levinas and the insightsthat his philosophy can offer to film studies. The collection features an internationalselection of contributors, and includes Levinas specialists as well as film scholars. Thereis no easy bond to be forged between this philosopher and film, and the possibility ofmaking this connection remains open to interrogation throughout some of the articles.But by taking Levinas to the cinema, while tracking the cinematic aspects of his thinking,all of the contributors address this hitherto occluded relation in generative ways, andeach creates a critical opening for future research in the field. (shrink)

In recent years, scholars of Jewish politics have invested political hopes in the revival of “political imagination.” If only we could recapture some of the imaginativeness that early Zionists displayed when wrestling with questions of regime design, it is argued, we might be able to advance more compelling “solutions” to the Israeli-Palestinian conflict. Yet how does one cultivate political imagination? Curiously, scholars who rehearse the catalogue of regimes that Jews have historically entertained seldom pose this question. In this Article, I (...) revisit a historical episode—the appropriation of diasporic historical narratives by Zionists in mandatory Palestine—in an effort to cultivate a richer political imaginary. I analyze the labor Zionist deployment of Simon Dubnow’s influential master narrative, focusing on a 1926 speech in which David Ben Gurion depicts the autonomist regime that he advocates as a variation upon diasporic political practices. On my reading, this episode illustrates the dilemmas that confront thinkers who invest political hopes in regime design. To realize the promise that new political configurations may emerge from reflections upon Jewish history, I argue, we must develop a new account of political agency, once foundational assumptions of the nation-state have been suspended. (shrink)

Experimental filmmaker Rose Lowder is an intricate explorer of perception. Many of her exquisite silent short films feature flowers that are scrutinized frame by frame in shots that appear to have layers, as well as volume, and to quiver between simultaneity and succession. Yet these perceptual palimpsests that present almost too much for the eye to take in also reveal an as yet unexplored relation to imagination. Informed by ecological principles and foregrounding floral beauty, Lowder's Bouquets create a striking bond (...) between perceptual and imaginative space. This article draws upon twentieth-century phenomenological accounts of perception before delving into earlier historical discussions of beauty in nature and in art, and bringing out connections to moral philosophy and feminist ecophilosophy, in order to understand how the beautiful entwines with ecological concern in the perceptual-imaginative space of her films. (shrink)

The debate over abortion tends to be framed as life versus choice. Yet, neither pole matches the actual experiences of women, especially women of colour and poor women. Using the hermeneutical circle from the perspective of Christian liberation theology, this article argues that beginning with the voices of those marginalized in the debate leads us to a broader conversation of reproductive justice, which requires an analysis of reproduction as a whole. The article focuses on what constrains the ability of women (...) and men to choose whether to have children, across the spectrum from contraception to abortion to fetus selection. (shrink)

The Aldine edition of Galen’s works, prepared by humanists anxious to replace the medieval Latin translations with a purely Greek text, certainly represents an advance in scholarship. However, widespread anti-Arabic prejudices of the time precluded most humanists, including the Aldine editors, from perceiving anything of value in the Latin Galenic textual tradition, which was characterized as representing a Galen that had passed through the corrupting influence of Arabic. This paper considers the cost to the medical tradition of ignoring Arabic in (...) the Aldine edition of 1525, and thereafter. Several examples of passages from the Arabo-Latin Galen are compared with the Aldine, and their differences are considered and evaluated with regard to their impact on medical knowledge. The conclusion is drawn that, although there were some real corruptions in the Arabo-Latin tradition, in the main it contained useful variant readings, which might have been used to the profit of Greek philology, as well as to the advancement of Galenic scholarship. (shrink)

The privacy and security rules of the Health Insurance Portability and Accountability Act of 1996 emphasize taking steps for protecting protected health information from unauthorized access and modification. Nonetheless, even organizations highly skilled in data security that comply with regulations and all good practices will suffer and must respond to breaches. This paper reports on a case study in responding to an important breach of the confidentiality and integrity of identifiable patient information of the Kaiser Internet Patient Portal known as. (...) From the perspective of theories about highly reliable organizations, effective health information security programs must respond resiliently to as well as prospectively anticipate security breaches. (shrink)